Research & Development
BioCircuit is driving innovation in electrical neural interfacing, focusing on advanced nerve monitoring, stimulation, and neurorehabilitation. Explore our research projects currently in development.
Neural
Interfacing
Non-invasive monitoring and control of nerve and muscle activity
BioCircuit’s bioelectronic platform was designed in response to these challenges.
Peripheral nerves convey sensory and motor signals between the brain/spinal cord and the rest of the body. Improved capabilities for “tapping in” to this nerve activity enhance the ability to diagnose and treat disease. Unfortunately, accessing these small neural signals is technically difficult and further complicated by person-to-person differences in anatomy.
The Challenge
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Specialized skin-surface electrode arrays can be quickly placed to provide broad coverage of the target nerve.
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Custom multichannel electronics and algorithms provide a high-definition view of underlying nerve activity and feedback-driven targeting of nerves for activation.
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The tools and software delivering these capabilities are designed for reliability, consistency, and practical ease-of-use.
These developing systems reflect BioCircuit Technologies' commitment to addressing critical healthcare challenges and advancing innovation. They seek to provide deeper insights into operant conditioning research and represent a critical step toward improving patient outcomes.
Reflex Operant Conditioning (ROC) System
BioCircuit, in collaboration with NCAN and MUSC, is developing an integrated ROC system to transform spasticity management.
Built on BioCircuit’s core bioelectronics platform, this system combines multichannel biosignal measurement with closed-loop, multiplexed electrical stimulation using custom, noninvasive electrode arrays.
A pilot clinical trial (NCT05094362) is currently investigating the system’s impact on spasticity management in patients with chronic incomplete SCI.
THE CHALLENGE
Spasticity poses a significant challenge for individuals living with spinal cord injuries (SCI), impacting mobility and quality of life.
THE OPPORTUNITY
Reflex Operant Conditioning has demonstrated its potential to reduce spasticity within controlled laboratory environments.
Customizable Electrode Arrays
The demands of modern neural and biomedical research require precision and flexibility. Our electrode arrays are engineered for multisite stimulation and recording, offering exceptional versatility for complex applications.
Currently in development, these arrays are fully customizable to address the unique needs of researchers and clinicians, empowering breakthroughs across a spectrum of neural and biomedical challenges. BioCircuit Technologies is committed to delivering advanced tools that push the boundaries of innovation.
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Supported by NIH NINDS
BioCircuit Technologies’ developments are proudly supported by the National Institutes of Health (NIH).
This research is supported by NIH NINDS U44NS114420
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